Immunology
Research and Excellence
Welcome to the Immunology Service at Ruber Internacional Hospital!
We are dedicated to diagnosing and treating a variety of conditions related to the immune system, offering specialized care in congenital or acquired immunodeficiencies, complex autoimmune diseases, immunological causes of infertility, hematological cancers, and genetic diagnosis of immune system disorders. Our team of experts is committed to your health and well-being, providing a comprehensive and advanced approach to the diagnosis, treatment, and follow-up of these conditions.
We leverage cutting-edge technology and the latest advances in clinical research to provide the highest level of care. Our immunology specialists work closely with other medical professionals to ensure multidisciplinary and personalized care tailored to your specific needs. On this page, you will find information about our services and our immunology experts.
Your well-being is our priority. If you have any questions or need to schedule an appointment, please do not hesitate to contact us.
An expert and state-of-the-art approach to improving your health and well-being.
- Team of Dr. Silvia Sánchez-RamónTeam Leader: Dr. Silvia Sánchez-RamónHospital Ruber Internacional, Centro Médico Paseo de la HabanaSpecialty: Clinical Immunology91 387 53 78 / 91 457 77 64
Experience and Research in Immunology
Our immunology specialists are distinguished by their extensive experience and outstanding research contributions in the field. Their dedication and expertise have positioned us at the forefront of research and treatment for conditions related to reproductive immunology, immunodeficiencies, and autoimmune diseases.
Reproductive Immunology Unit
Our Reproductive Immunology Unit is a national and international leader in the study of reproductive failure caused by inflammatory or alloimmune immunological factors. In our unit, we provide diagnosis, treatment, and follow-up for various conditions affecting reproductive health. Some of the primary conditions we address include:
- Recurrent miscarriage: Refers to the repeated loss of pregnancies before the fetus reaches viability (generally before 20 weeks of gestation). It is considered recurrent after three or more consecutive spontaneous miscarriages.
- Unexplained infertility: Also known as idiopathic infertility, it refers to the inability of a couple to conceive after at least one year of regular, unprotected sexual intercourse without any identifiable cause of infertility.
- Recurrent implantation failure after assisted reproductive treatments: Occurs when several attempts to transfer embryos via assisted reproductive techniques (such as IVF or ICSI) fail to result in successful implantation in the uterus.
- History of preeclampsia: A pregnancy complication characterized by high blood pressure and organ damage, such as to the liver and kidneys, after 20 weeks of gestation. A history of preeclampsia indicates that the woman has experienced this condition in a previous pregnancy.
- Intrauterine growth restriction (IUGR): A condition where a fetus does not reach the expected size for its gestational age. It can result from various causes and impact the baby's development and health in the womb.
- Unexplained preterm birth: Refers to the birth of a baby before completing 37 weeks of gestation without a clear cause identified for the preterm delivery. Prematurity can have significant implications for the baby’s health and development.
Immunodeficiencies
We have extensive experience in diagnosing, treating, and monitoring patients with primary and secondary immunodeficiencies caused by immunosuppressive treatments, hematological cancers, or other factors. Additionally, we provide comprehensive vaccination counseling, ensuring that our patients receive the most up-to-date and appropriate recommendations for their individual needs.
Autoimmune Diseases
We offer specialized advice on complex autoimmune or inflammatory diseases referred by other medical specialists. Our multidisciplinary approach enables us to address these conditions comprehensively and effectively, provide expert guidance, and work collaboratively to improve our patients' quality of life.
Medical Excellence and Cutting-Edge Research
An immunodeficiency is a condition in which the immune system is weakened or compromised, resulting in a reduced ability to defend against infections and diseases. It is essential for individuals with immunodeficiencies to receive specialized medical care, as the key to successful treatment lies in proper diagnostic evaluation and the design of effective preventive strategies.
Our team of immunologists is dedicated to utilizing the latest advances in diagnostic procedures and innovative treatments to manage primary and secondary immunodeficiencies. Primary immunodeficiencies are genetic in origin, whereas secondary immunodeficiencies are caused by external factors such as autoimmune diseases or cancer. We provide personalized treatments and comprehensive diagnostic evaluations.
- Congenital Immunodeficiencies: Our service specializes in the diagnosis, treatment, and follow-up of primary immunodeficiencies, which are genetic disorders that affect the immune system’s ability to protect the body from infections and diseases. We offer comprehensive genetic counseling to identify and understand these conditions, which can encompass up to 300 associated diseases. Our team of experts is committed to delivering personalized treatments to improve the quality of life for these patients and minimize the risk of infections and complications.
- Secondary Immunodeficiencies: These develop due to external factors and are more common than primary immunodeficiencies. They are often a result of other diseases such as diabetes, HIV, or various types of hematological cancers, including leukemia, myeloma, or lymphoma. Our medical team works to adjust and manage treatments to reduce the risk of infections and other complications.
At the Immunology Service of Ruber Internacional Hospital, we provide cutting-edge medical care focused on the individual needs of each patient and work tirelessly to improve their quality of life.
Do not hesitate to contact us to schedule an appointment or to obtain additional information about our Immunology Service.
We employ a multidisciplinary approach to address infertility issues. We conduct specific studies to identify potential immunological causes that may impact conception, pregnancy, and its progression. Treatments vary depending on the underlying cause and include immunomodulatory therapies, immunosuppressive treatments, or assisted reproductive techniques.
During pregnancy, the immune system plays a crucial role, and certain inflammatory causes can negatively affect the process, leading to issues such as recurrent miscarriages, prematurity, or embryo implantation failure. Some immunological problems, such as antiphospholipid syndrome or autoimmune endocrine disorders, may be associated with these challenges.
To diagnose these issues, our team uses blood tests to rule out antibodies and inflammatory markers and to assess HLA-C compatibility between the baby and the mother.
Our clinical immunology team is a pioneer and a reference in Europe in the field of reproductive immunology. Additionally, we remain at the forefront of clinical research to stay up to date with the latest therapies available to improve your chances of conception and achieving a healthy pregnancy.
Experts in Reproductive Immunology.
At the Immunology Service of Ruber Internacional Hospital, we offer cutting-edge diagnostic techniques:
- Clinical Exome Sequencing: Used for the diagnosis of genetic diseases, including cancer, diabetes, and cystic fibrosis. This diagnostic method provides a comprehensive analysis of the patient’s DNA.
- Metagenomics: Applied for studying a community of microorganisms living in our bodies. It allows for exhaustive surveillance of infectious diseases and the transmission pathways of pathogens.
- Microbiome Analysis: Performed on blood, stool, or endometrial samples.